The Kennel Club Genetics Centre at the Animal Health Trust has identified a genetic mutation which causes progressive retinal atrophy (PRA) in Golden Retrievers, and developed a DNA test to identify carriers.

PRA is a retinal disease which causes loss of vision and leads to blindness. PRA cannot be treated - the most successful way to combat the inherited condition is to identify dogs that carry the mutation and develop informed breeding strategies.

The new DNA test has been developed following the identification of the mutation which causes the most common form of PRA among Golden Retrievers in Europe - known as GR_PRA1. The mutation which causes a second form of PRA is still to be identified.

Cathryn Mellersh, Head of Canine Genetics at the AHT, said: "Our research shows that this mutation is present in the UK Golden Retriever population, so it's likely that several hundred new carriers are being born each year and that Golden Retrievers are invariably going blind as a result.

"This new DNA test will enable breeders to learn whether their dogs are carriers of the mutation. This, in turn, will enable them to make better informed breeding decisions and therefore produce puppies which will not go blind as a result of this mutation."

Mike Townsend, Chairman of the Kennel Club Charitable Trust, said: "This is a real breakthrough and one which we hope will help to prevent blindness in many Golden Retrievers in the years to come. Every dog deserves to lead a healthy, happy life and it is important that we do all we can to ensure that future generations are given this opportunity. Our knowledge about inherited diseases in dogs is growing every day and the development of DNA tests such as this one allows breeders to ensure that the healthiest genes are passed down through the generations."

The DNA test for PRA follows the success of the AHT's DNA test launched last year to identify carriers of a mutation that causes primary lens luxation. This test identifies carriers in more than 12 breeds of dog, including Miniature Bull Terriers, Jack Russell Terriers, Parson Russell Terriers and Patterdale Terriers. To date more than 6,500 samples from 36 countries have been tested.

The Kennel Club Charitable Trust has committed £1.2 million to the Kennel Club Genetics Centre at the AHT, which will undertake research into approximately 25 inherited diseases over the next five years, facilitating the creation of further diagnostic tests which will improve the health and welfare of generations of dogs.

Full information on the Golden Retrievers PRA DNA test, and information on ordering sample kits, will be available from http://www.aht.org.uk/ from 15 November.

PS: Whilst you're here, take a moment to see our latest job opportunities for vet nurses.