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Sileo provides a micro-dose of dexmedetomidine hydrochloride, a selective alpha-2 adrenoceptor agonist which Zoetis says helps a dog calm down or remain calm yet fully functional in situations involving fear-eliciting sounds.
Sileo is presented as an oromucosal gel formulation in a 3ml oral syringe that can be used to apply multiple doses.
Zoetis says that its user-friendly application means that, once prescribed, it can be given by the dog owner and used only when needed for each noise anxiety event. It takes effect within 15 - 60 minutes and last for 2-3 hours. Should the fear-eliciting noise continue, further doses can be given at two hour intervals up to a total of five times during each noise event.
The company says that even when the full dosing limit is used, the dog will remain functional during treatment; the clinical effects of dexmedetomidine are dose-dependent and the anxiolytic effect is reached before the sedative effect.
Animal behaviourist, Jon Bowen BVetMed DipAS (CABC) MRCVS, said: "Fear of seasonal loud noises such as fireworks, thunder and gunshots are known to affect around 50% of the UK dog population but the prevalence of fears of other everyday noises and the extent to which those fears contribute to nuisance and problem behaviour in dogs is something we are researching at the moment. Sileo is ideal as an acute anxiolytic for planned or expected events such as fireworks or thunder, but it has an even wider range of potential applications in planned events that involve stressful noise exposure including travel, social gatherings and even visits to the vet."
Sileo is available to order now via your veterinary wholesaler.
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